Description
Synthetic Peptide for Kisspeptin Receptor (KISS1R / GPR54) Research
Technical Overview
Kisspeptin-10 (KP-10) 10mg is a synthetic decapeptide compound developed for laboratory research involving neuroendocrine signaling, GnRH/LH/FSH release pathways, receptor interaction analysis, and controlled experimental investigation. In research settings, this peptide is commonly utilized for studying KISS1R (also known as GPR54) binding affinity, downstream G-protein coupled receptor signaling in hypothalamic models, and related biochemical mechanisms.
Kisspeptin-10 is the C-terminal active fragment of the parent Kisspeptin protein encoded by the KISS1 gene. It binds the KISS1R receptor with sub-nanomolar to low-nanomolar affinity in both rodent and human receptor models. The peptide family was initially identified for tumor metastasis suppressor properties (KISS1 = “Kisspeptin Suppressor Sequence”) before its central role in reproductive endocrinology was discovered through KISS1R loss-of-function studies.
Specifications
Sequence: Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂
Molecular Formula: C₆₃H₈₃N₁₇O₁₄
Molecular Weight: 1302.45 g/mol
Purity: ≥ 99%
CAS: 374675-21-5
Form: Lyophilized powder
Research Use Only
This product is intended for laboratory research purposes only and is not for human or veterinary use, diagnostic procedures, or therapeutic application.
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